Not long back cancer was considered an incurable disease and still some cases arise when it cannot be cured. Medical science recent development in the field of ultra sound technology has led to a development of a technology called HIFU (high intensity focused ultrasound) and it has been found very useful in postate cancer treatment . HIFU (sometimes also called as FUS or HIFUS) is a highly precise medical procedure using high-intensity focused ultrasound to heat and destroy pathogenic tissue rapidly. Since quite a high intensity of ultrasound waves are used and it cause heat, it can damage other healthy tissues as well, so to avoid this the whole process is computerized and made sure its done accurately and HIFU is targeted on pathogenic tissues only. These ultrasonic waves cause the rise in temperature within the tissue (65° to 85°C) destroying the diseased tissue by coagulation necrosis. Here with the help of MRI, the whole procedure is accurately performed and this is also sometimes referred as Magnetic Resonance guided Focused Ultrasound (MRgFUS).Using this technique prostate, liver, and boner cancer is treated successfully and trials on other types of cancer are also underway. HIFU devices like ablatherm are mostly used in such treatment due to their high precision and safety. More advanced machines with 3D imaging function etc are also available for those areas where even more precision is required like in brain tumor cases.